mac and cheese meatloaf casserole baked with melted cheese and fresh herbs

Mac and Cheese Meatloaf Casserole for Comfort Food Lovers

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Created on February 6th, 2026 at 01:00 pm

A family friendly comfort casserole that brings two favorites together

Some comfort food cravings are simple. Others feel impossible to satisfy with just one dish. This mac and cheese meatloaf casserole was created for those moments when you want something hearty, cozy, and familiar, but also fun enough to feel special. It brings together two classic comfort foods and turns them into a single, family friendly casserole that works beautifully for busy weeknights and relaxed dinners alike.

Meatloaf has always been a dependable dinner, especially for families who want something filling and affordable. Mac and cheese, on the other hand, is pure comfort, creamy, nostalgic, and universally loved. When these two come together in casserole form, the result is a dish that feels indulgent without being complicated. Everything bakes together into a warm, layered meal that feels generous and satisfying.

This recipe is designed for family friendly dinner bowls, where scooping, sharing, and customizing plates is part of the experience. It is comforting, filling, and approachable, making it a reliable option when you want to please everyone at the table.

homemade mac and cheese meatloaf casserole baked with melted cheese and herbs

Quick Facts

Prep Time: 30 minutes
Cook Time: 45 minutes
Total Time: 1 hour 15 minutes
Yield: 6 servings

Kitchen Utensils

This casserole is made with simple, modern kitchen tools that make preparation smooth and cleanup manageable.

  • Large mixing bowl
  • Medium saucepan
  • Whisk
  • Baking dish
  • Large pot for pasta
  • Colander
  • Measuring cups and spoons
  • Wooden spoon or silicone spatula

Why This Casserole Works for Family Friendly Dinner Bowls

Family friendly dinner bowls are all about flexibility and comfort. This casserole fits perfectly into that concept because it combines protein and pasta in one cohesive dish while still allowing room for customization. Some family members may scoop more mac and cheese, while others prefer extra meatloaf in their bowl.

The casserole format also makes serving easy. Everything is baked together, so there is no need to juggle multiple pots at the table. The flavors are familiar and mild, making it appealing to kids, while the hearty texture and cheesy richness satisfy adults. It is a meal that feels cozy and generous, without feeling chaotic or overwhelming to prepare.

Ingredients

For the Meatloaf Layer

  • Ground beef
  • Breadcrumbs
  • Milk
  • Large eggs
  • Garlic, minced
  • Onion, finely chopped
  • Italian seasoning
  • Salt
  • Black pepper

For the Mac and Cheese Layer

  • Elbow macaroni
  • Butter
  • All purpose flour
  • Milk
  • Cheddar cheese, shredded
  • Mozzarella cheese, shredded
  • Salt
  • Black pepper

Optional Topping

  • Extra shredded cheese
  • Chopped fresh parsley

Instructions

These instructions are written clearly and with enough detail so the dish comes together smoothly, even if you are cooking from a printed page.

  1. Preheat your oven to 375°F and lightly grease a baking dish. Set it aside so it is ready once the layers are prepared.
  2. Bring a large pot of salted water to a boil. Add the elbow macaroni and cook until just al dente. Drain and set aside.
  3. In a large mixing bowl, combine the ground beef, breadcrumbs, milk, eggs, garlic, onion, Italian seasoning, salt, and black pepper. Mix gently until just combined. Avoid overmixing to keep the meatloaf tender.
  4. Press the meatloaf mixture evenly into the bottom of the prepared baking dish, forming a compact but not overly tight layer.
  5. Bake the meatloaf layer for about 20 minutes, just until it begins to set. This step ensures the casserole holds its shape later.
  6. While the meatloaf layer bakes, prepare the cheese sauce. Melt butter in a medium saucepan over medium heat.
  7. Whisk in the flour and cook for about one minute, stirring constantly, until a smooth paste forms.
  8. Slowly pour in the milk while whisking, making sure no lumps form. Continue cooking until the sauce thickens slightly.
  9. Reduce the heat and stir in the shredded cheeses until fully melted and smooth. Season with salt and black pepper.
  10. Combine the cooked macaroni with the cheese sauce, stirring until all the pasta is evenly coated.
  11. Remove the baking dish from the oven and carefully spread the mac and cheese layer evenly over the partially baked meatloaf.
  12. Sprinkle extra cheese on top if desired.
  13. Return the dish to the oven and bake for an additional 20 to 25 minutes, until the top is bubbly and lightly golden.
  14. Let the casserole rest for 10 minutes before serving so the layers set properly.

Tips & Substitutions

  • Use lean ground beef for a lighter casserole.
  • Swap cheddar for a blend of cheeses if desired.
  • Whole wheat pasta can be used for added fiber.
  • Add finely chopped vegetables to the meatloaf for extra nutrition.

Storage & Make Ahead

This mac and cheese meatloaf casserole is excellent for leftovers. Once cooled, store it in an airtight container in the refrigerator for up to four days.

To reheat, warm individual portions in the microwave or reheat the entire dish in the oven until heated through. This casserole can also be frozen. Wrap portions tightly and freeze for up to two months. Thaw overnight before reheating for best texture.

When This Dish Shines Most

This casserole is perfect for family dinners, casual gatherings, or nights when comfort food feels like the right answer. It is hearty enough to stand on its own but also pairs well with a simple salad or steamed vegetables.

Because it combines two beloved dishes, it often becomes a repeat request, especially in households with kids. It is familiar, filling, and easy to love.

A Comfort Casserole Worth Sharing

Mac and cheese meatloaf casserole is the kind of recipe that brings people together. It feels nostalgic, generous, and comforting, without requiring complicated steps or ingredients.

Save this dish for evenings when you want something warm, filling, and guaranteed to please. It is comfort food done in a way that fits real life.

FAQ

Can I prepare this casserole ahead of time?
Yes, this casserole works very well as a make ahead meal. You can assemble the entire dish, cover it tightly, and store it in the refrigerator for up to one day before baking. When ready to bake, allow it to sit at room temperature briefly and add a few extra minutes to the baking time if needed.

Is this recipe suitable for kids?
Absolutely. The flavors are familiar and mild, making it very appealing to children. The combination of meatloaf and mac and cheese is especially popular with younger eaters, and the casserole format makes it easy to serve manageable portions.

Can I freeze leftovers?
Yes, leftovers freeze well. Portion the cooled casserole into airtight containers or freezer bags. Freeze for up to two months. Thaw overnight in the refrigerator before reheating to maintain the best texture.

What sides go well with this dish?
Simple sides work best. A green salad, steamed broccoli, or roasted vegetables balance the richness of the casserole without competing with its flavors.

How do I keep the casserole from drying out?
Avoid overbaking and allow the dish to rest after baking. The cheese sauce and meatloaf moisture will keep the casserole creamy and tender when handled gently.

mac and cheese meatloaf casserole baked with melted cheese and fresh herbs

Mac and Cheese Meatloaf Casserole for Comfort Food Lovers

Zac, the creator of Eat Every Slice, smiling in a kitchen while wearing an apron, specializing in Italian-American recipes.Zac
This mac and cheese meatloaf casserole combines two classic comfort foods into one family friendly baked dish. Tender meatloaf and creamy macaroni and cheese come together for a hearty, satisfying dinner.
Prep Time 30 minutes
Cook Time 45 minutes
Total Time 1 hour 15 minutes
Course Dinner
Cuisine American-Italian
Servings 6 servings

Equipment

  • Large mixing bowl
  • Large pot
  • Medium saucepan
  • Whisk
  • Baking dish

Ingredients
  

Meatloaf Layer

  • 1 1/2 lb ground beef lean preferred
  • 1 cup breadcrumbs
  • 1/2 cup milk
  • 2 large eggs
  • 2 cloves garlic minced
  • 1 onion finely chopped
  • 1 tsp Italian seasoning

Mac and Cheese Layer

  • 12 oz elbow macaroni cooked al dente
  • 3 tbsp butter
  • 3 tbsp all purpose flour
  • 2 cups milk warmed
  • 1 1/2 cups cheddar cheese shredded
  • 1 cup mozzarella cheese shredded

Instructions
 

  • Preheat the oven to 375°F. Lightly grease a baking dish so the casserole releases easily after baking.
  • Bring a large pot of salted water to a boil. Cook the macaroni until just al dente so it does not become mushy when baked later. Drain and set aside.
  • In a large bowl, combine ground beef, breadcrumbs, milk, eggs, garlic, onion, and Italian seasoning. Mix gently just until combined to keep the meatloaf tender.
  • Press the meatloaf mixture evenly into the bottom of the prepared baking dish. Do not pack it too tightly.
  • Bake the meatloaf layer for 20 minutes so it sets slightly and holds its shape in the casserole.
  • While the meatloaf bakes, melt butter in a saucepan over medium heat. Whisk in flour and cook briefly to form a smooth base.
  • Slowly whisk in warmed milk, continuing to stir until the sauce thickens and becomes smooth.
  • Reduce heat and stir in shredded cheeses until fully melted and creamy. Season lightly with salt and pepper.
  • Combine the cooked macaroni with the cheese sauce, stirring gently until all pasta is coated evenly.
  • Remove the baking dish from the oven and carefully spread the mac and cheese layer over the partially baked meatloaf.
  • Return the dish to the oven and bake for an additional 20 to 25 minutes, until the top is bubbly and lightly golden.
  • Allow the casserole to rest for 10 minutes before serving so the layers set and portions hold together.

Notes

Make ahead: Assemble the casserole up to one day in advance and bake when ready.
Storage: Refrigerate leftovers for up to 4 days.
Freezing: Freeze cooled portions for up to 2 months.
Reheating: Reheat gently to keep the cheese sauce creamy.
Keyword cheesy meatloaf bake, comfort food casserole, easy comfort dinner, family friendly dinner bowls, mac and cheese meatloaf casserole

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