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baked mac and cheese meatloaf casserole with golden cheese topping and fresh herbs

Baked Mac and Cheese Meatloaf Casserole for Easy Dinners

Chef Roberto, an Italian-American cuisine expert from Eat Every Slice, smiling while holding a plate of freshly made pasta garnished with basil.Roberto
This baked mac and cheese meatloaf casserole is a comforting Italian-inspired weeknight dinner. A tender meatloaf base and creamy macaroni and cheese layer bake together into a satisfying and family friendly meal.
Prep Time 30 minutes
Cook Time 45 minutes
Total Time 1 hour 15 minutes
Course Dinner
Cuisine American-Italian
Servings 6 servings

Equipment

  • Large mixing bowl
  • Large pot
  • Medium saucepan
  • Whisk
  • Baking dish

Ingredients
  

Meatloaf Layer

  • 1 1/2 lb ground beef lean preferred
  • 1 cup breadcrumbs
  • 1/2 cup milk
  • 2 large eggs
  • 2 cloves garlic minced
  • 1 onion finely chopped
  • 1 tsp Italian seasoning

Mac and Cheese Layer

  • 12 oz elbow macaroni cooked al dente
  • 3 tbsp unsalted butter
  • 3 tbsp all purpose flour
  • 2 cups milk warmed
  • 1 1/2 cups cheddar cheese shredded
  • 1 cup mozzarella cheese shredded

Instructions
 

  • Preheat the oven to 375°F. Lightly grease a baking dish so the casserole releases easily after baking and portions lift out cleanly.
  • Bring a large pot of salted water to a rolling boil. Cook the macaroni until just al dente so it keeps its structure during baking. Drain thoroughly and set aside.
  • In a large mixing bowl, combine ground beef, breadcrumbs, milk, eggs, garlic, onion, and Italian seasoning. Mix gently just until combined to avoid compacting the meat.
  • Press the meatloaf mixture evenly into the prepared baking dish, forming a flat, even layer without packing it too tightly.
  • Bake the meatloaf layer for about 20 minutes so it sets slightly and can support the mac and cheese layer without mixing.
  • While the meatloaf bakes, melt butter in a saucepan over medium heat. Whisk in flour and cook for about one minute to remove the raw flour taste.
  • Slowly whisk in warmed milk, stirring constantly until the sauce thickens and becomes smooth and creamy.
  • Lower the heat and stir in the shredded cheeses until fully melted. Season lightly with salt and pepper and remove from heat.
  • Combine the cooked macaroni with the cheese sauce, stirring gently so every piece of pasta is evenly coated.
  • Remove the baking dish from the oven and carefully spread the mac and cheese evenly over the partially baked meatloaf layer.
  • Return the casserole to the oven and bake for 20 to 25 minutes, until the top is bubbly and lightly golden.
  • Let the casserole rest for 10 minutes before serving. This allows the layers to set and makes slicing easier.

Notes

Make ahead: Assemble the casserole up to one day in advance and bake when ready.
Storage: Refrigerate leftovers for up to 4 days.
Freezing: Freeze cooled portions for up to 2 months.
Reheating: Reheat gently to keep the cheese sauce creamy.
Keyword baked mac and cheese meatloaf casserole, comfort food casserole, easy weeknight casserole, family dinner bake, healthy italian weeknight dinners