Go Back
Sliced Italian-style meatloaf casserole with cheesy pasta layers in a white baking dish

Italian Inspired Meatloaf Casserole with Cheesy Pasta

Chef Roberto, an Italian-American cuisine expert from Eat Every Slice, smiling while holding a plate of freshly made pasta garnished with basil.Roberto
A hearty Italian inspired casserole combining tender meatloaf with creamy, cheesy pasta. Perfect for family dinners and cozy evenings.
Print Recipe Pin Recipe
Prep Time 30 minutes
Cook Time 45 minutes
Total Time 1 hour 15 minutes
Course Casserole, Dinner
Cuisine American Italian Inspired
Servings 6 servings
Calories 525 kcal

Equipment

  • Mixing Bowl
  • Saucepan
  • Whisk
  • Baking dish

Ingredients
  

Meatloaf Layer

  • 1 1/2 pounds ground beef
  • 1 egg
  • 3/4 cup breadcrumbs
  • 1/2 cup milk
  • 1/4 cup grated onion
  • 1 teaspoon garlic powder
  • 1 teaspoon salt
  • 1/2 teaspoon black pepper
  • 1/3 cup ketchup

Cheesy Pasta Layer

  • 2 cups short pasta dry
  • 3 tablespoons butter
  • 3 tablespoons all purpose flour
  • 2 cups milk
  • 2 cups shredded mozzarella or cheddar cheese
  • 1/2 teaspoon salt

Instructions
 

  • Preheat oven to 375 degrees Fahrenheit and grease a baking dish.
  • Mix meatloaf ingredients gently and press evenly into the baking dish.
  • Cook pasta until just tender and drain.
  • Prepare cheese sauce and fold in pasta.
  • Spread cheesy pasta over meatloaf and bake until bubbly and golden.
  • Rest casserole before slicing and serving.

Notes

Allow the casserole to rest before slicing so the layers set properly.
Keyword cheesy pasta casserole, comfort food casserole, family dinner bake, italian meatloaf casserole